We're not going to be able to start a clinical trial in a year, but I think it's a real opportunity to understand the intricacies of the biology involved
For example, a meta-analysis of 31 randomized, controlled trials reports that the most common side effects observed in the hGH studies and their respective incidences were [16]: Soft tissue edema: 50% Insulin resistance: 22% Arthralgias: 21% Carpal tunnel syndrome: 19% These side effects are transient and usually subside as the patient gets used to the therapy
its functional and metabolic
Knownwells Business Model: Rewiring Weight Management for Sustainable Scale Knownwell isnt another telehealth startup chasing GLP-1 prescriptions
However, extended endurance exercise may result in reduced cardiac function, a phenomenon known as cardiac fatigue (43)
Advertisement While semaglutide works to mimic GLP-1 hormones, tirzepatide (like Mounjaro and Zepbound) is considered a dual agonist