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(2015) Treatment of vitamin B12 deficiency-methylcobalamine

High-performance liquid chromatography quantification of GSH/GSSG, 3-NT and 3-CT To evaluate biomarkers of oxidative stress and damage by high-performance liquid chromatography (HPLC), approximately 200 mg of tissue was minced and homogenized in 500 l of ice-cold phosphate-buffered saline

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doi: 10.1080/17425255.2021.1925249

They found that the activation of Nrf2 in liver cells of PBC patients was enhanced after UDCA treatment and thioredoxin (TRX) and thioredoxin reductase 1 (TrxR1) protein significantly increased (Figure 5) (Shearn et al., 2019)

Our review provides insights into the relevant regulatory mechanisms of ferroptosis, examining the impact of ferroptosis-related factors from both physiological and pathological perspectives