Accessed 22/2/2025 Nauck MA, Jensen TJ, Rosenkilde C, Calanna S, Buse JB
A) all generic cos were very low on their GLP1 forecast before the launch - a few 10s of crores at best in the 1st year eg A top co in India had a 10cr first yr sales forecast and is set to do a multiplier of that On top of that fewer than expected cos have launched B) online sales which is the biggest area of growth on GLP1s (pharmacies / Telehealth) doesnt get captured and so is direct sales
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More importantly, combined with drug-encapsulating silk fibroin NPs, cartilage-targeting WYRGRL peptide, and sustained-release soluble MNs, we designed and prepared the cartilage-targeting MNs/GLP-1RAs@NPs-WYRGRL which offers a novel and highly translatable strategy for precise, efficient, and low-side-effect therapy in the management of rheumatoid arthritis
The cells were then lysed to quantify the amounts of albumin inside, or washed and further incubated in serum-free medium for an additional 3 h to allow for release of recycled albumin back into the medium
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