10.1038/nri3041 113 GlodzikL.RandallC.RusinekH.de LeonM
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Reduced appetite suppression, unexpected side effects, or injection site reactions that differ from your normal experience could indicate that the medication has degraded
Deficiency is linked to increased migraine frequency, muscle cramping, and heightened stress response
Dropping back to your previous dose level might resolve side effects while maintaining some treatment benefit