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Renal Impairment Initiation of XIGDUO XR is not recommended in patients with an eGFR below 45 mL/min/1.73 m and is contraindicated in patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m) or end-stage renal disease [see DOSAGE AND ADMINISTRATION , CONTRAINDICATIONS and WARNINGS AND PRECAUTIONS ]

Often includes B vitamins, anti-nausea and anti-inflammatory medications to ease headaches and nausea

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Understanding how the pen works, how it is administered and the principles behind dosing helps explain its role in ongoing investigational studies

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Your provider may recommend the Precision Peptide Genetic Test after the first month to refine your long-term treatment strategy and ensure you're on the optimal compound for your biology