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Drug interactions: Concurrent use with other performance-enhancing substances, supplements, or prescription medications has not been evaluated and may produce unpredictable interactions

American Journal of Physiology

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Recently, the European Commission classified obesity as a chronic disease and regardless of age, a weight loss of 5% has traditionally been regarded as clinically relevant, with 10% now emerging as the minimum to substantially lower the risk of poor outcomes (Tahrani & Morton, 2022)

And then oral and transdermal, it didn't seem to make a difference