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CAFs-induced ECM remodeling results in increased tissue stiffness and the activation of mechanotransduction signaling pathways, such as integrin-FAK and YAP/TAZ signaling, thereby conferring increased malignancy to tumors (121)

For instance, saying, "I feel nauseous sometimes" gives the doctor very little useful information

Multi-dose vials that are accessed repeatedly over days or weeks accumulate contamination risk with each needle insertion

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Ongoing new research underscores the need for a multifaceted approach that extends beyond the active drugs lifecycle