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Once activated, this mechanism leads to PINK1 stabilization on the mitochondrial outer membrane and to Parkin recruitment from cytosol

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Reduced BDNF availability may in turn limit TrkB phosphorylation and attenuate downstream PI3K/Akt and MAPK/ERK signaling (Numakawa and Kajihara, 2023)

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Production simulations were conducted using a LFMiddle Langevin Integrator in a NPT ensemble (simulation parameters summarized in Extended Data Table 3) 77

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