TLR4 belong to the family of patter recognition receptors (PRRs) and is expressed in several immune cells, such as monocytes, macrophages, and Kupffer cells, but also endothelial cells, adipocytes, and hepatocytes
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Then I think there was probably also this: is it important to treat obesity or should we rather focus on cardiovascular disease and diabetes and some of the other diseases that have more comorbidities maybe or when you look at it are more acutely serious
