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The use of prazosin, an 1-adrenergic receptor blocker, showed that the ability of GLP-1RAs to reduce TNF- in plasma was disrupted, signifying the vital role of 1-adrenergic receptors in the anti-inflammatory action of GLP-1RAs

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Additional information Peer review information Nature thanks Martin Bergo, Marcus Conrad, Sarah-Maria Fendt and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

This combination works by targeting different brain chemical systems and may provide more comprehensive symptom relief

Specifically, the RQ values were consistently lower when athletes took LC under the experimental protocol, indicating a shift toward fat oxidation and sparing muscle glycogen, a crucial aspect of endurance performance

G.JonesR.KwonS.BoncianiG.ThieronH.ChandlerT.et al