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To assess whether GGCT metabolic enzymatic activity regulates changes in the TCA cycle, we predicted the structure of GGCT and constructed a mutant (E98A) in PC3 and DU145 cell lines [20] (Fig

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The experimental animal feed for the iron overload mouse model (Table S1) was synthesized by Jiangsu Medicience Biological Medicine Co., Ltd (Jiangsu, China)