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Naringin attenuates oxidative stress, inflammation, apoptosis, and oxidative DNA damage in acrylamide-induced nephrotoxicity in rats
In IPF, GSH levels are significantly reduced, contributing to a pro-oxidant environment that promotes fibroblast proliferation and ECM accumulation [120]
Apigenin has been shown to inhibit RelB expression and nuclear translocation, affecting DC maturation and antigen presentation, which alters T cell responses from pro-inflammatory Th1/Th17 phenotypes to regulatory T cells (Tregs), thus alleviating inflammatory responses (113)
This disease may affect any age group, but it is most prevalent in individuals in the age groups 15-30 and 50-70 yr1
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