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While these proteins are important antioxidative enzymes in mammals, the plant forms have a different catalytic mechanism and several independent studies strongly suggest that they preferentially use thioredoxins as reductant (Herbette et al

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Typically, UGA codons serve as signals for translation termination (20)

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Consequently, further studies are required to clarify these possible connections

VPA poisoning may on occasion cause severe toxicity and can very rarely be fatal