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Eli Lilly, the maker of Mounjaro and Zepbound, is urging the court to impose stricter diagnostic proof requirements in the ongoing GLP-1 gastroparesis litigation

Holst's scientific work has focused on the regulatory peptides of the pancreas and the gut and their importance in the regulation of the functions of the GI-tract and metabolism, with particular focus on blood glucose and appetite regulation, obesity and diabetes

These drugs have also been associated with improvements in blood pressure and cholesterol levels, although its uncertain if these benefits are directly due to the medication or the resulting weight loss

Gut hormones that signal fullness (like CCK and GLP-1) work more effectively when estrogen is present

There is an inflammatory IL-6/STAT3 signaling pathway that is persistently activated in malignancy to protect tumor cells from immune cell attack (Wang et al., 2018)