Compared to individuals without steatosis, patients with NASH have an increased incidence of ASCVD (HR 1.37, 95% CI 1.101.72) [102] and fatal and nonfatal MACEs (OR: 1.64, 95% CI 1.262.13) [103]
FDX1 has the ability to directly interact with copper ions present in plaques, thereby triggering protein-induced toxic stress
It has a shorter half-life, so effects may fade faster unless doses are maintained
As key regulators within the post-transcriptional control network, miRNAs significantly contribute to the pathogenesis of atherosclerosis (Raskurazhev et al., 2022)
## Storage After Reconstitution - **Refrigerate** at 36-46 degrees F (2-8 degrees C) immediately after reconstitution - **Use within 28-30 days** - **Protect from light** -- store in the original box or wrap in foil - **Never freeze** reconstituted solution - **Check before each use** -- if cloudy, discolored, or containing particles, discard ### Before Reconstitution (Unreconstituted Powder) - Refrigerate or store at controlled room temperature per the label - Check expiration date - Keep dry and protected from moisture ## Injection Technique ### Preparing Your Dose 1
Leave to air-dry for 30 seconds