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When I say we normally make all the carnitine we need, theres a rare genetic inborn error of metabolism that affects as many as one in 40,000 births, which can result in a need for dietary carnitine

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The glutamic-acid substitution sterically prevents binding to IGF-binding proteins (IGFBPs), leaving a far larger fraction of the peptide free to engage the IGF-1 receptor (IGF-1R)

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