It must be combined with lifestyle changes known to promote healthy weight management, like Mediterranean-style eating and strength training
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But, as Marks points out, 'Unfortunately amino-acid sequencing was not then as reliable as it later became and in the case of GIP was wrong
4 Therefore, the use of a GLP-1 receptor agonist (exenatide, liraglutide) can be used as monotherapy or dual therapy in those with an A1C of 6.5% to 7.5%
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If insulin signalling matters as much in the brain as that work suggests, GLP-1 drugs may not be incidentally helping the brain