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Furthermore, non-steroidal anti-inflammatory drugs (NSAIDs) are widely used medications against pelvic pain and dysmenorrhea, usually administered even before a definitive diagnosis

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Springer Link , doi:10.1007/s00394-019-01919-4

For example, the general applications of adeno-associated virus-based gene therapy are hampered by pre-existing humoral immune responses against the viral vectors [350,351,352], which for some viral serotypes occur in up to 60% of the population because of early-life infections [353, 354]

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Side effects are rare but may include mild irritation at the injection site