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GGCT channels Gln flux for GSH synthesis and Glc anaplerosis into the TCA cycle ROS act as signaling molecules that regulate mitochondrial function, with mitochondrial morphology intrinsically linked to core processes, including the TCA cycle and oxidative phosphorylation

It signals fullness to the brain, slows stomach emptying, and helps the pancreas release insulin when blood sugar rises

Last updated April 2020

Growing up in New York, Unger completed his medical degree at Columbia University and then directed a project to detect diabetes for the US Public Health Services

Longobardi L, et al

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