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However, some clinical evidences have presented conflicting evidence, suggesting that the AEs of GLP-1 RAs may not be as severe or widespread as initially thought

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Rudolph P, Tronnier M, Menzel R, Moller M, Parwaresch R

This cognitive-computational shift appears to mimic the effects of neuropsychiatric symptoms on motivational cognition in other clinical groups

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On the individual level, its terrible, even without other NCDs there is a huge stigma attached to being obese