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The elucidation of glucoraphanins biosynthetic pathway and its regulatory mechanisms, particularly the master transcription factor MYB28, has enabled targeted genetic interventions

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They did not have Type 2 Diabetes (T2D) but did have Chronic Kidney Disease (CKD) which they defined as estimated glomerular filtration rate (eGFR) 25 and urine albumin-to-creatinine ratio (UACR) 30

The Theta class is composed of TmGst8 and TmGst9