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Collectively, these findings suggest that coagulation factors, specifically ADAMTS13 and vWF, represent promising non-invasive biomarkers and potential therapeutic targets in the diagnosis and management of endometriosis, highlighting their role in hypercoagulability and chronic inflammation observed in the disease (70)

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Suryantari et al., 2020), thereby it can inhibit the conversion of 13,4-dihydroxyphenylalanine to melanin (Tse, 2010) and further induce melanin necrosis, that can avoid the melanogenesis process