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Description

Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NFB/AMPK/NLRP3 axis

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Anti-nuclear antibody

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After binding to its cell membrane receptor, TNF activates NF-B in the following sequence: (a) phosphorylation of the inhibitor of NF-B (IB-) by IKK

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With dose-proportional pharmacokinetics, higher doses produced stronger effects across these markers

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This prevents the medication from backing up into the esophagus, which is even more important when digestion is slow

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