Because the fat layer there is far less consistent from person to person, which the article says makes depth harder to predict and absorption more variable
J Invest Dermatol 144(7):1479-1490 e14
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Abstract Plant glutathione S-transferases (GSTs) are ubiquitous and multifunctional enzymes encoded by large gene families
Through rigorous scientific experiments, Zhao et al
In such a protocol, it's common to administer the BPC-157 locally to the ankle and the TB-500 systemically in the abdomen, leveraging the theoretical strengths of each compound's primary mechanism of action