Its concentration matters, too little and sterility may not be maintained over the full use period, too much and it can interact with the peptide or cause injection site irritation
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The following changes may indicate that the product has degraded and should not be used: Cloudiness or haziness in the solution, which may suggest protein aggregation or contamination Visible particles or floaters suspended within the liquid Discolouration any shift towards brown, orange, or notably deeper yellow tones Crystalline deposits along the walls of the vial or cartridge, which may indicate freezing has occurred Leaking, cracked, or damaged packaging or devices, which compromise sterility It is worth noting that some changes in stability may not be visible to the naked eye, yet the product's potency may still have been compromised by improper storage
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There are cases where semaglutide got ruined due to improper storage