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The number of reps significantly increased at week 6 only in the LCR group (2.00 n, 95% CI, 0.39, 3.60) but not in the PLA group (0.90 n, 95% CI -0.77, 2.59)

When levels are low, inflammation can become chronic and systemic, contributing to numerous health challenges

Pharmacogenetic indicators, such as polymorphisms in DPYD, TYMS, GSTP1, and ABCC2, have been linked to toxicity in patients undergoing fluoropyrimidine and oxaliplatin-based treatments [269, 270]

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For CII assessment, 20 l succinate (100 mM), ADP (10 mM), rotenone (10 M) and plasma membrane permeabilizer (10 nM) were added to port A, 22 l oligomycin (10 g ml 1 ) was added to port B and 25 l antimycin A (A0149