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Therefore, mutations in parkin gene increase the susceptibility to glutamate neurotoxicity predisposing to the early onset neurodegeneration of PD

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If you have malabsorption syndrome (such as short bowel syndrome, certain bariatric surgery patients, chronic pancreatitis, or celiac disease that severely impairs nutrient uptake), you might need these injections indefinitely to prevent recurrent deficiencies

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doi: 10.18632/aging.204007