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However, due to the various forms of ghrelin and their effects, it is currently challenging to establish clear relationships with GH secretion in PWS (113)

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Most Common Side Effects (Experienced by Many Users): Nausea (often most severe in first 2-4 weeks or after dose increases) Diarrhea Vomiting Constipation Abdominal pain Indigestion Fatigue Injection site reactions Belching Gastroesophageal reflux (heartburn) These side effects are generally most intense when starting treatment or increasing doses

doi: 10.3390/nu7105404

The peptide safety guide provides additional detail on managing these risks