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Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication

This leads to multiple future therapeutically relevant opportunities: Obesity Treatment : Modulating SPTBN1 expression or function could provide a novel therapeutic strategy to combat obesity by inhibiting the Caspase-3SPTBN1 axis and its downstream effects

doi: 10.1007/s00394-012-0380-y

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