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IM injection: Doses up to 5 mL can be administered undiluted as a slow intramuscular injection over approximately 3 minutes

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489,496 Thirdly, NMNAT1 does not change the NAD + biosynthesis, but prevents the SARM1-dependent NAD + depletion caused by injury, which is important for axon degeneration

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Elevated levels of oxidative stress markers have been consistently reported in ME/CFS, including malondialdehyde (MDA), isoprostanes, 8-OH-deoxyguanosine, 2,3 diphosphoglyceric acid, thiobutyric acid, and protein carbonyls

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