No, at controlled dosages, reported effects are typically mild such as temporary muscle tightness or water retention and are reversible under appropriate medical oversight
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While these findings are promising, human clinical trials are still needed to confirm its effectiveness in treating cardiovascular injuries (7)
Its active form, 1,25-dihydroxyvitamin D, crosses the bloodbrain barrier and binds to vitamin D receptors (VDRs) widely expressed in areas critical for cognition, such as the hippocampus, cortex, and substantia nigra (58, 59)
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