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According to a study published in Frontiers in Pharmacology, intramuscular administration of vitamin B12 produces a faster increase in serum levels compared to oral routes, although both methods are effective in restoring normal cobalamin levels in patients with deficiency

The profound cellular exhaustion, the unpredictable cognitive fog, and the heavy burden of post-exertional malaise are not just "in your head"they are the direct result of measurable, physiological disruptions in your body's mitochondrial and antioxidant defense systems

GSH levels were not impacted either, and cysteine levels were only slightly reduced (Additional file 3)

Hossain MA, Mayo AK, Ghoshal A, Taft-Benz S, Anderson E, Morales NL, et al

Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas

B12 can be injected intramuscularly to give a more sustained and powerful energy boost than oral vitamins