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There is some polymorphism for the glutathione synthetase enzyme, so some cases of HAGMA with 5-oxoprolinemia occur later in life under particular metabolic stress, suggesting a previously unrecognized genetic defect [5]

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Recommendations typically suggest 1.0-1.6 grams of protein per kilogram of body weight daily, with higher amounts for those actively trying to preserve or build muscle

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Fernandez AM, Jimenez S, Mecha M, Dvila D, Guaza C, Vitorica J, Torres-Aleman I (2012) Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimers pathology