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Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis

A recent study described the severe digestive issues accompanied with taking GLP-1 agonists

Late 2024 had already seen the launch of the first generic exenatide, and in August 2025 the FDA approved the first generic version of liraglutide (Saxenda) for weight loss, with Teva launching immediately

Oral formulations enter the bloodstream more gradually, potentially easing initial nausea for sensitive patients

LEADER, STEP 2, SUSTAIN-6, PIONEER 6) showed that metformin use did not increase the incidence or severity of gastrointestinal adverse events or drive treatment discontinuation

doi: 10.1007/s11060-007-9417-0