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Retrieved July 30, 2018 from title=Chicago]Rockefeller UniversityLack of a Single Molecule May Indicate Severe and Treatment Resistant Depression. (accessed July 30, 2018).[/cbtab][/cbtabs] Abstract Acetyl-l-carnitine deficiency in patients with major depressive disorder The lack of biomarkers to identify target populations greatly limits the promise of precision medicine for major depressive disorder (MDD), a primary cause of ill health and disability