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Research suggests T4 may stimulate angiogenesis, enhance collagen deposition, support keratinocyte and endothelial migration, and reduce inflammatory cytokine signaling through modulation of pathways such as NF-B

They help reduce inflammation by shifting M1 macrophages (pro-inflammatory) to M2 macrophages (anti-inflammatory) and decreasing levels of inflammatory cytokines like TNF-, IL-6, and IL-1