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Well, the consensus leans towards peptides first

Malinow MR, Duell PB, Williams MA, Kruger WD, Evans AA, Anderson PH, Block PC, Hess DL, Upson BM, Graf EE et al

Pioglitazone, a diabetes medication, may benefit selected patients with biopsy-proven NASH, but is also specialist-led and off-label , with potential risks including weight gain, fluid retention, heart failure, and increased fracture risk

The combination of peptides with other therapies, such as gene therapy or immunotherapy, holds the potential for more effective treatments for complex diseases

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The effects of vasoactive intestinal peptide in neurodegenerative disorders