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In addition, ferroptosis acts as a systemic stress response, capable of propagating intercellularly through mechanisms such as exosome-mediated signaling, phagocytic dysfunction, and immune evasion

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Deficiencies in B12 can directly lead to nerve damage and worsen symptoms of diabetic neuropathy.65 While most people can get adequate B12 through diet (meat, fish, dairy, fortified cereals), certain medications including metformin and proton pump inhibitors can impair absorption and raise the risk of deficiency

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Epithalon has a relatively short plasma half-life, estimated at several minutes following subcutaneous injection

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