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Yes the NNMT pathway is not sex-specific

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It also works to help your body convert food into glucose which supplies the necessary energy used throughout your day

Unlike fat-soluble vitamins (A, D, E, and K) which are stored in adipose tissue and the liver for extended periods, water-soluble vitamins generally dissolve in water and are not stored in large quantities

When a compound average effect is only 2 kilograms over 12 weeks, many individual participants likely saw minimal to no change, while a smaller subset may have responded more strongly, pulling the average up