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For risk-averse individuals or those with complex medical histories, this established safety profile is reassuring

- An ingredient also used in the treatment of melasma, known for its excellent melasma improvement effects by inhibiting melanin production

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Sustained elevation of IGF-1 is associated, in observational studies of acromegaly (a disease of GH excess), with increased risk of several cancers including colorectal and breast

10.1016/j.jnutbio.2015.08.017 124 JiangH.ZhangC.HeW

Together, we can ensure that the science is sound, the data is trustworthy, and the results are meaningful