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Novel class of bivalent glutathione S-transferase inhibitors

(File this under: Things you know already.) Youre probably using a mild facial cleanser, maintaining a healthy skin barrier with a daytime and nighttime moisturizer, and using sun protection every single day

Compounds such as alpha-chloroacetamide-based inhibitors achieve this by covalently binding to a cysteine residue in the SAM-binding pocket of NNMT 202

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Artesunate induces melanoma cell ferroptosis and augments antitumor immunity through targeting Ido1