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ELISA assays showed that BV2-metformin-loaded PLGA lowered pro-inflammatory markers (TNF-, IL-6) and boosted anti-inflammatory markers (IL-4, IL-10) in both the brain tissue and blood samples 19

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Different pathways have been recently identified to play a key role in the escape of the immune system in senescence, highlighting the potential development of significant senolytic therapies in the future (Fig

When GH is infused locally into one leg of a hypophysectomized (GH-deficient) rat, that leg grows significantly longer than the other (323)