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Hot flushes during treatment may relate to hormonal changes, perimenopause, dietary modifications, or other concurrent health conditions

Unlike GLP-1, GIP has not been found to possess a similar neural signaling mechanism for decelerating gastric emptying (54, 162)

On the other hand, Methyl Sulphonyl Methane, better known as MSM, is a naturally occurring sulphur compound that MSM may plays a role in the synthesis of glutathione (GSH) [14] one of the most important intracellular antioxidants [15], through its transulfuration pathway [14]

GIP (glucose-dependent insulinotropic polypeptide) is another incretin-related hormone with roles in nutrient handling and energy metabolism

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Additionally, the coincidence between glutamate dysregulation and microglial activation was assessed by evaluating the activated microglial marker Iba-1