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Buyon JP, Petri MA, et al

7 This is crucial as psoriasis is associated with an increased risk of cardiovascular events 8 and a patient may be taking medications that are metabolised by CYP/P-glycoprotein mechanisms

Methylfolate speeds up methylation and neurotransmitter production. If this happens: reduce the dose or stop temporarily, try niacin (50100 mg) to use up excess methyl groups, switch to folinic acid, switch methylcobalamin to hydroxocobalamin, and ensure adequate potassium, magnesium, and glutathione. Whats wrong with folic acid

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Rosen, P