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10.3389/fphys.2020.615351 40 HyattH

These lipotropic compounds may support how the liver processes fat and how the body uses stored energy sources

Morita K, Wang F, Jahn K, Yan Y, Durruthy-Durruthy R, Parikh A, Matthews J, Little L, Gumbs C, Zhang J, Song X, Thompson E, Patel K, Bueso-Ramos C, DiNardo C, Ravandi F, Jabbour E, Andreeff M , Cortes JE, Konopleva M, Garcia-Manero G, Kantarjian H, Eastburn D, Futreal PA, Beerenwinkel N, Takahashi K

Women are at higher risk, with an incidence of 1420 per 100,000 compared to 630 per 100,000 in men

Researchers have shown that a TFR-mediated increase in iron uptake in GCs induces the release of ROS, mitochondrial autophagy, and lipid peroxidation (108)

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