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Although prospective studies specifically targeting PCOS + MASLD with pregnancy outcomes as the primary endpoint are currently lacking, a robust inference can be drawn based on the pathophysiological framework of MASLD and evidence from the general population: proactively identifying and reducing MASLD and ectopic fat load prior to pregnancy may be a key step in improving both periconception outcomes and long-term prognosis (68, 76)

early studies showed that ITCs block new blood vessel formation and epithelialmesenchymal transition (EMT) in tumors (122)

[DOI] [PubMed] [Google Scholar] 65.Lenzi A, Sgro P, Salacone P, Paoli D, Gilio B, Lombardo F, et al

When this receptor is turned on the body releases growth hormone in a pulsed way

Such test would be helpful for selecting patients with high levels of OS who are candidates for AOX therapy, and for monitoring the treatment response

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