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S.ApostolopoulouM.TianY.TempleS

EClinicalMedicine 90 , 103680 (2025)

elegantly demonstrated that neural stem cell secretomes inhibit microglial activation via BDNF/VEGF signaling, but their work neglected gastrointestinal dysbiosis, overlooking the bidirectional crosstalk now recognized as central to ASD pathophysiology [42]

They have proven to be incredibly effective for what they were originally intended to be used for and still are: managing type 2 diabetes, and now for weight loss

Inflammatory cytokines such as IL-1 downregulate occludin expression selectively in vitro and in vivo

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