503b glp-1 FDA Enforcement Compounded GLP-1 crackdown? 🚨 FDA

Referring to compounding as personalized was consistent with established legal requirements

#DDW2025 OBESITY AND IBD by @EdwardLoftus2 Obesity is a chronic inflammatory statue Adipose tissue is not biologically inert (TNFa, IL-6, IL-8, leptin, adiponectin) Postulated role in the pathogenesis of IBD Potential risk factor for adverse outcomes Trends in BMI among IBD patients at diagnosis in Olmsted County, Doubling of obesity rates in 20 years in CD and UC (Johnson AM JCC 2021 and J Clin Gastro 2024) Obese patients more likely to have a colonic phenotype

Amlodipine and valsartan tablets may be used to lower high blood pressure (hypertension) in adults Amlodipine and valsartan tablets have not been studied in children under 18 years of age

95% CI (0.66, 3.11), P = 0.045)

They should be used to identify questions to ask before enrollment, not to estimate medical results or current service times

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