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MDPI Hsieh MJ et al

First, the glutamate cysteine ligase (GCL) catalyzes the formation of a dipeptide constituted by glutamate and cysteine, and then the GSH synthetase catalyzes the addition of glycine to form GSH[38], the former being the rate-limiting step

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This is a critical safety step that goes beyond just testing the raw ingredient

A recent BMJ editorial, Malnutrition with use of GLP-1 agonists is an underestimated real world harm, highlights how these therapies can cause unintended nutritional consequences that remain poorly recognised in practice (BMJ 2025)

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