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These are often the first indicators of improved delta sleep quality and overnight recovery

PMID: 24366116 Zondervan KT, et al

It binds what must leave, restores what must regenerate, and stays active where cumulative burden likes to hide

Sleep timing, nighttime awakenings, and morning alertness are common markers to monitor.

Again, it should be really mild with Volbella - especially as compared to other fillers

We can indirectly assume ozone therapy influenced synthesis and release of cytokines (18,19) in such a way that a change from Th2 to Th1 (IL-2, IFNg) cytokine pattern occurs, or ozone therapy acted as Th2 cytokine inhibitor